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Patrick M. Boyle's CardSS Lab | UW Bioengineering

New CardSS Lab Research Published in JAHA: Our First Foray into Explainable ML!

Congratulations to Savannah Bifulco, whose second lead-author original research paper has been published in JAHA.

In this study, we use SHAP Analysis (devised brilliantly by CS researchers at our own institution!) to predict the behavior of reentrant activity in computational simulations from geometric features extracted from LGE-MRI alone.

Summary figure from doi: 10.1161/JAHA.123.030500. "A, Ablation in PsAF can transform substrate that favors FR perpetuation into one that is more conducive to ARs. B, Nonconductive tissue properties, characterized by high surrounding fibrosis (indicated by the blue line above the dashed boundary) or an intermediate perimeter/area (indicated by the red line above the dashed boundary) are indicative of arrhythmogenic substrate in postablation models. AR indicates anchored reentry; FR, functional reentry; and PsAF, persistent atrial fibrillation."

Cool beans! Way to go Savannah!