We’re pleased to share a new paper led by Surbhi Sharma, in collaboration with Lindsay Edwards (Duke) and colleagues across Seattle Children’s, Fred Hutch, and other children’s hospitals: “Early prediction of cardiomyopathy in pediatric cancer survivors using echocardiographic video-based deep learning” (also available on PubMed Central). Cardiomyopathy (CM) is a leading cause of late death in childhood cancer survivors, but it is often caught only after irreversible cardiac remodeling. We asked whether a 3D convolutional neural network, applied to routine…
Category: News
New paper in Heart Rhythm: adding epicardial fat to image-based atrial models makes AF drivers easier to induce
We’re excited to share a new paper from our collaboration with Dr. Nazem Akoum’s group in UW Cardiology, led by Dr. Yaacoub Chahine: “Substrate Comprising Fibrosis and Epicardial Adipose Tissue-Associated Electrophysiological Remodeling Can Sustain Atrial Fibrillation Drivers: Insights from Image-Personalized Computational Simulations” in Heart Rhythm (also available on PubMed Central). Image-based atrial models usually account for fibrosis but not for the epicardial adipose tissue (EAT) surrounding the atria, and arrhythmia often can’t be induced in them at all. Using MRI…
Exciting New Research from the CardSS Lab: Can AI-enhanced ECGs help predict cardiac arrest?
We are very proud to announce the publication of new research from the CardSS Lab and our collaborators on the use of artificial intelligence-enhanced electrocardiography and electronic health record data to predict out-of-hospital cardiac arrest. Congratulations to first author Dr. Surbhi Sharma and thank you to our outstanding collaborators, including co-senior authors Dr. Neal Chatterjee and Dr. Shaan Khurshid. This paper, published in JACC: Advances, tackles a major challenge in cardiovascular medicine: how can we identify people at elevated risk…
Tanishka Goplani Heads to Switzerland to Study Abroad
We are very proud to share that Tanishka Goplani has been admitted into the Engineering Switzerland study abroad program with the University of Washington for Early Fall 2026! In Lausanne and Geneva, she will be studying the fundamentals of electrical engineering at EPFL — Swiss Federal Technology Institute of Lausanne, Europe’s most cosmopolitan technical university renowned for pioneering research and innovation. She will also engage with Swiss researchers to learn more about ongoing scientific discoveries and visit the CERN facility…
Exciting New Research from the CardSS Lab: How does fibrotic remodeling affect atrial biomechanics?
We are very proud to announce the publication of a major step forward in our understanding of the relationship between disease-related (fibrotic) remodeling of the heart and biomechanics of atrial contraction. Congratulations to first author Dr. Åshild Telle and thank you to our dear friend and collaborator, co-senior author Dr. Christoph Augustin. This paper is a big deal for our lab for several reasons. First, it include an implementation of fractional factorial design (FFE), a “Design of Experiments” technique Pat spends…
New Research on How Different Fibrotic Patterns Alter Cardiac Tissue Mechanics
We are excited to announce a new CardSS Lab paper, entitled “Mechanical Modeling of Cardiac Fibrosis with Explicit Spatial Representation of Cellular Structure and Collagen Alignment” by Dr. Åshild Telle, Pat, and other collaborators. The study reveals that replacement fibrosis greatly amplifies the level of stress on remaining cells and softens directional stiffness. Interstitial fibrosis, on the other hand, primarily stiffens the tissue stretch without altering anisotropy. The publisher has posted a direct link to a publicly-available PDF version of the…